“Consider: a single light-year is an inconceivable abyss. Denumerable but inconceivable. At an ordinary speed – say, a reasonable pace for a car in megalopolitan traffic, two kilometers per minute – you would consume almost nine million years in crossing it. And in Sol’s neighborhood, the stars averaged some nine light-years part. Beta Virginis was thirty-two distant. Nevertheless, such spaces could be conquered.”
In “Tau Zero” by Poul Anderson.
Yeah I'm aware of the twin paradox and how Special Relativity alone doesn't account for the returning twin being younger; at the time I remember wondering specifically whether one of the main criticism of Tau zero (i.e. that the crew of the ship should observe the universe as being slower relative to them while they're accelerating, not sped up as it is in the book) was on the nose. Not that most people think that special relativity is simple, but in fact it is even trickier than is apparent the first time you meet it.
If you're into stuff like this, you can read the full review.